Endocrine Abstracts

Introduction: Most recent ATA thyroid nodule/DTC guidelines recommend thyroidectomy without prophylactic CND for small (T1 or T2), non-invasive, clinically node-negative PTC (cN0). However, some studies have suggested an association between the BRAFV600E mutation and the risk of nodal disease. Moreover, BRAF V600E mutation have recently showed significant association with recurrence in solitary intrathyroidal PTC between 2 and 4 cm (pT2) making suitable a more aggressive treat...

Introduction: Abnormal thyroid function is the most common disease in endocrinology and its screening of made by plasmatic (TSH), followed by (fT4) determination if abnormal. (fT3) determination is only used when pathological (TSH) and normal (fT4) are found, even if there is no evidence supporting this procedure, apart from the greater technical difficulty of measuring (fT3) due to its lower plasma concentration.Material and Methods: Observational retro...

Background: PHPT is the leading cause of hypercalcemia in outpatients. Its clinical presentation varies from asymptomatic forms to renal or bone complications. The only curative treatment is surgical resection, and delayed diagnosis can lead to serious morbidity.Objective: Identify the presence of PHPT at least one year prior to referral to endocrinology consultation. Secondly, determine whether diagnostic delay leads to increased complications.<p cl...

Current guidelines suggest sonographic follow-up in thyroid nodules smaller than 10 mm with intermediate or highly suspicious features as ultrasound-guided FNAC has poor results in these nodules, and the risk of non-diagnosed thyroid carcinoma is very low. CNB has proved superior to repeated FNAC in case of insufficient or indeterminate first FNAC.Objective: Evaluate diagnostic accuracy of CNB in nodules smaller than 10 mm with intermediate or high suspi...

sTg is universally accepted as the best marker of disease status in DTC. Its presurgical serum level may suggest the presence of distant metastasis in case of very high level, but the correlation between its level and the characteristics of the tumour is yet to be defined.Objective: To evaluate preoperative thyroglobulin as predictor of DCT features.Methods: Preoperative sTg was measured in patients operated for DTC between 2011&#1...